ABSTRACT
Introduction: Osteoarthritis is a chronic degenerativecondition of joint often associated with pain, deformity,disability in movement, and reduction in the quality of life.Study aimed to assess the utilization and efficacy of Plateletrich plasma (PRP), for the management of early kneeosteoarthritis.Material and methods: Patients presenting with symptomaticearly knee osteoarthritis were included in the study. Theyunderwent infiltration of 5 ml PRP into the knee joint. Patientsare evaluated 6 months after the procedure with Visualanalogue scale (VAS) and range of motion assessment.Result: In our study of 150 patients with early osteoarthritisof knee, 58.6% presented with Kellgren lawrance grade 2 andremaining were grade 1 osteoarthritis. At 1 month follow up,the procedure gave excellent results in 32% patients and goodresults in 26% patients, better with Kellgren lawrance grade1 osteoarthritis. At 3 month follow up, PRP infiltration gaveexcellent results in 47.3% patients with early osteoarthritisand good results in 37.3%. At 6 month follow up, resultswere excellent in 47.3% of patients and good results in 24.6%patients. Of the 71 patients showing excellent results, 57.7%had Kellgren Lawrance grade 1 osteoarthritis. Poor responsefollowing PRP infiltration is shown by only 2 patientsConclusion: Our study results support the application ofautologous PRP as a safe and effective method in the treatmentof the early stages of knee osteoarthritis. Significant clinicalimprovement was seen with 6 months of follow-up.